High-resolution genomic analysis of human mitochondrial RNA sequence variation.

High-resolution genomic analysis of human mitochondrial RNA sequence variation. Journal: Science| Pages: 413-415 |Date: April 2014 | Authors: Hodgkinson A, Idaghdour Y, Gbeha E, Grenier JC, Hip-Ki E, Bruat V, Goulet JP, de Malliard T, Awadalla P. Mutations in the mitochondrial genome are associated with multiple diseases and biological processes; however, little is known about the Read more about High-resolution genomic analysis of human mitochondrial RNA sequence variation.[…]

Recombination affects accumulation of damaging and disease-associated mutations in human populations.

Recombination affects accumulation of damaging and disease-associated mutations in human populations. Journal: Nature Genetics| Pages: 400-404 |Date: April 2015 | Authors: Julie G Hussin, Alan Hodgkinson, Youssef Idaghdour, Jean-Christophe Grenier, Jean-Philippe Goulet, Elias Gbeha, Elodie Hip-Ki, Philip Awadalla Many decades of theory have demonstrated that, in non-recombining systems, slightly deleterious mutations accumulate non-reversibly, potentially driving the extinction of many asexual species. Non-recombining Read more about Recombination affects accumulation of damaging and disease-associated mutations in human populations.[…]

A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility

A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility Journal: Eur J Hum Genet | Pages: 682-689 | Date: June 2012 | Authors: Sapkota Y, Robson P, Lai R, Cass CE, Mackey JR, Damaraju S. Genome-wide association studies for breast cancer have identified over 40 single-nucleotide polymorphisms (SNPs), a subset of which Read more about A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility[…]

Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)

Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009) Journal: Cancer Causes Control | Pages: 463-468 | Date: March 2011 | Authors: Boffetta P, Colditz GA, Potter JD, Kolonel L, Robson PJ, Malekzadeh R, Seminara D, Goode EL, Yoo KY, Demers P, Gallagher R, Prentice R, Yasui Y, O’Doherty K, Petersen GM, Ulrich CM, Csizmadi I, Read more about Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)[…]

Exploring statistical approaches to diminish subjectivity of cluster analysis to derive dietary patterns: The Tomorrow Project.

Exploring statistical approaches to diminish subjectivity of cluster analysis to derive dietary patterns: The Tomorrow Project. Journal: Am J Epidemiol | Pages: 956-967 | Date: April 2011 | Authors: Lo Siou G, Yasui Y, Csizmadi I, McGregor SE, Robson PJ. Dietary patterns derived by cluster analysis are commonly reported with little information describing how decisions are made at each Read more about Exploring statistical approaches to diminish subjectivity of cluster analysis to derive dietary patterns: The Tomorrow Project.[…]

Hours spent and energy expended in physical activity domains: results from the Tomorrow Project cohort in Alberta, Canada

Hours spent and energy expended in physical activity domains: results from the Tomorrow Project cohort in Alberta, Canada Journal: Int J Behav Nutr Phys Act | Date: October 2011 | Authors: Csizmadi I, Lo Siou G, Friedenreich CM, Owen N, Robson PJ. BACKGROUND: Knowledge of adult activity patterns across domains of physical activity is essential for the planning Read more about Hours spent and energy expended in physical activity domains: results from the Tomorrow Project cohort in Alberta, Canada[…]

Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility.

Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility. Journal: Hum Genet. | Pages: 529-537 | Date: October 2011 | Authors: Sehrawat B, Sridharan M, Ghosh S, Robson P, Cass CE, Mackey JR, Greiner R, Damaraju S. Previous genome-wide association studies (GWAS) have shown several risk alleles to be associated with breast cancer. However, the Read more about Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility.[…]

Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies.

Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies. Journal: Int J Epidemiol | Pages: 1383-1393 | Date: September 2012 | Authors: Fortier I, Burton PR, Robson PJ, Ferretti V, Little J, L’Heureux F, Deschênes M, Knoppers BM, Doiron D, Keers JC, Linksted P, Harris JR, Lachance G, Boileau C, Pedersen NL, Hamilton CM, Hveem Read more about Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies.[…]

The Canadian Partnership for Tomorrow Project: building a pan-Canadian research platform for disease prevention.

The Canadian Partnership for Tomorrow Project: building a pan-Canadian research platform for disease prevention. Journal: CMAJ | Pages: 1197-1201 | Date: August 2010 | Authors: Borugian MJ, Robson P, Fortier I, Parker L, McLaughlin J, Knoppers BM, Bédard K, Gallagher RP, Sinclair S, Ferretti V, Whelan H, Hoskin D, Potter JD. As the proportion of the population over Read more about The Canadian Partnership for Tomorrow Project: building a pan-Canadian research platform for disease prevention.[…]

Are physical activity levels linked to nutrient adequacy? Implications for cancer risk

Are physical activity levels linked to nutrient adequacy? Implications for cancer risk Journal: Nutr.Cancer | Volume: 66 (2) | Pages: 214-224|Date: 2014 | Authors: Csizmadi I, Kelemen LE, Speidel T, Yuan Y, Dale LC, Friedenreich CM, Robson PJ. Cancer prevention guidelines recommend a healthy body mass index, physical activity, and nutrient intake from food rather than supplements. Read more about Are physical activity levels linked to nutrient adequacy? Implications for cancer risk[…]