Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer

Authors: Jacob Nearing, Vanessa DeClercq, Morgan Langille Journal: Nature Biofilms and Microbiomes Abstract: The human microbiome has been proposed as a potentially useful biomarker for several cancers. To examine this, we made use of salivary samples from the Atlantic Partnership for Tomorrow’s Health (PATH) project and Alberta’s Tomorrow Project (ATP). Sample selection was divided into both Read more about Investigating the Oral Microbiome in Retrospective and Prospective Cases of Prostate, Colon and Breast Cancer[…]

Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases

Authors: Sheida Majouni, Jong Sung Kim, Ellen Sweeney, Erin Keltie, Syed Sibte Raza Abidi Ebook: Volume 294: Challenges of Trustable AI and Added-Value on Health Abstract: Chronic exposure to environmental arsenic has been linked to a number of human diseases affecting multiple organ systems, including cancer. The greatest concern for chronic exposure to arsenic is Read more about Applying Machine Learning to Arsenic Species and Metallomics Profiles of Toenails to Evaluate Associations of Environmental Arsenic with Incident Cancer Cases[…]

Harnessing the Power of Data Linkage to Enrich the Cancer Research Ecosystem in Canada

Authors: Robin Urquhart, Philip Awadalla, Parveen Bhatti, Trevor JB Dummer, Simon Gravel, Jennifer Vena, Riaz Alvi, Phillipe Broet, Cynthia Kendell, Victoria Kirsh, Guillaume Lettre, Kimberly Skead, Grace Shen-Tu, Ellen Sweeney, Donna Turner Journal: International Journal of Population Data Science Abstract: Objectives: We will enrich the cancer research ecosystem in Canada through linking cancer registry and Read more about Harnessing the Power of Data Linkage to Enrich the Cancer Research Ecosystem in Canada[…]

Arsenic Speciation and Metallomics Profiling of Human Toenails as a Biomarker to Assess Prostate Cancer Cases: Atlantic PATH Cohort Study

Authors: Erin Keltie, Kalli Hood, Yunsong Cui, Ellen Sweeney, Gabriela Ilie, Anil Adisesh, Trevor Dummer, Veni Bharti, Jong Sung Kim Journal: Frontiers in Public Health (Environmental Health and Exposome) Abstract: Chronic exposure to inorganic arsenic and trace metals has been linked to prostate cancer, and altered arsenic methylation capacity may have an important role in Read more about Arsenic Speciation and Metallomics Profiling of Human Toenails as a Biomarker to Assess Prostate Cancer Cases: Atlantic PATH Cohort Study[…]

Substituting bouts of sedentary behavior with physical activity: Adopting positive lifestyle choices in people with a history of cancer

Authors: Lee Ingle, Samantha Ruilova, Yunsong Cui, Vanessa DeClercq, Ellen Sweeney, Zhijie Michael Yu, Cynthia C. Forbes Journal: Cancer Causes and Control Abstract Purpose To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist Read more about Substituting bouts of sedentary behavior with physical activity: Adopting positive lifestyle choices in people with a history of cancer[…]

Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)

Journal: Cancer Causes and Control Authors: Rachel A. Murphy,  Maryam Darvishian, Jia Qi, Yixian Chen, Quincy Chu, Jennifer Vena, Trevor J. B. Dummer, Nhu Le, Ellen Sweeney, Vanessa DeClercq, Scott A. Grandy, Melanie R. Keats, Yunsong Cui, Philip Awadalla, Darren R. Brenner & Parveen Bhatti   Abstract Background Although smoking is the primary risk factor for lung cancer, 15–25% of lung cancers occur in never smokers. Emerging evidence suggests lifestyle Read more about Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)[…]

Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions

Authors: Vanessa DeClercq, Jacob T. Nearing, and Morgan G.I. Langille Journal: PLOS One Abstract Background: Commonly used medications produce changes in the gut microbiota, however, the impact of these medications on the composition of the oral microbiota is understudied. Methods: Saliva samples were obtained from 846 females and 368 males aged 35-69 years from a Canadian population Read more about Investigation of the impact of commonly used medications on the oral microbiome of individuals living without major chronic conditions[…]

Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry

Journal: Environmental Research Authors: Crystal L. Sweeney, Nathan K. Smith, Ellen Sweeney, Alejandro M. Cohen, and Jong Sung Kim Abstract: Human serum and urine samples were analyzed for a suite of nitrosatable pesticides and potentially carcinogenic pesticide-associated N–nitroso (PANN) compounds. Formation of PANN compounds may occur in vivo after consumption of food or water containing trace amounts of Read more about Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry[…]

The Impact of Reporting Magnetic Resonance Imaging Incidental Findings in the Canadian Alliance for Healthy Hearts and Minds Cohort

Journal: BMC Medical Ethics Authors: Judy M. Luu, Anand K. Sergeant, Sonia S. Anand, Dipika Desai, Karleen Schulze, Bartha M. Knoppers, Ma’n H. Zawati, Eric E. Smith, Alan R. Moody, Sandra E. Black, Eric Larose, Francois Marcotte, Erika Kleiderman, Jean-Claude Tardif, Douglas S. Lee, Matthias G. Friedrich on behalf of the CAHHM Study Investigators Abstract Read more about The Impact of Reporting Magnetic Resonance Imaging Incidental Findings in the Canadian Alliance for Healthy Hearts and Minds Cohort[…]

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses

Journal: Brain and Behavior Authors: Lonneke A. van Tuijl, Adri C. Voogd, Alexander de Graeff, Adriaan W. Hoogendoorn, Adelita V. Ranchor, Kuan-Yu Pan, Maartje Basten, Femke Lamers, Mirjam I. Geerlings, Jessica G. Abell, Philip Awadalla, Marije F. Bakker, Aartjan T.F. Beekman, Ottar Bjerkeset, Andy Boyd, Yunsong Cui, Henrike Galenkamp, Bert Garssen, Sean Hellingman, Martijn Huisman, Read more about Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses[…]